Jianghong Wang


  • ADVANTAGES
  • Good at the syntheses of organic compounds , function materials, medicines, polymers, and chemical analysis and the theoretical demonstration of literatures research.

  • BACKGROUND SUMMARY

  • Engaged in the syntheses of organic compounds, medicines, function materials and polymer for twelve years, chromatography analysis for three years.


  • ACHIEVEMENTS
  • Published over ten English articles, for example, Journal of Porphyrinns and Phthalocyanines(USA), Perking Transaction 1 (UK), Synthetic Metals(USA), Journal of Materials Science(2, USA) and Advanced Materials for Optics and Electronics (UK) and so on.

  • RESEARCH SUMMARY
  • Synthesis and characterization of Polydiacetylenes substituted with pyrimidine; novel electro-optic styrylthiophene chromophore monomers and corresponding polyurethane; Syntheses of some atypical antipsychotic drugs; Hepatocarcinogen; Phthalonitriles and Phthalocynanines; Sulfhydryl cross-linking reagent; Angiotensin-converting enzyme (ACE) inhibitor; Intermediate in the lipidation of proteins, Sphingomyelinase, Inhibitor of GSK-3(IC50=22nM), Metabolite of caffeine; N-Acetyl-L-carnosine,and so on

  • WORK EXPERIENCES
  • Chinese Academy of Sciences (1998-2000, Associate professor). University of Toronto, Canada(2000-2001, Postdoctoral); York University, Canada(2002, Postdoctoral), Toronto Resaerch Chemicals Inc. (Dec.,2003-August, 2004, Research Chemist), Orbital Biochemical Inc. (2004-present, Research Chemist)

    Sept.1996-July,1998: postdoctoral research under Prof. Yuquan Shen, Institute of Chemistry - the Chinese Academy of Sciences (ICCAS); Research subject: Synthesis and characterization of novel electro-optic styrylthiophene chromophore monomers and corresponding polyurethanes

    Sept.1998-Sept.2000: Research Group of nonlinear optical materials, Institute of Chemistry - the Chinese Academy of Sciences (ICCAS)/Beijing D-Venturepharm. T. Corp; Position: associate professor.

    Oct. 2000-Dec.2001: postdoctoral researcher,supervisor:
    Prof. Robert A. McClelland
    ,Department of Chemistry, University of Toronto, Canada; Research subject: Syntheses of clozapine-like antipsychotic drugs and their corresponding affinity numbers in vitro/ in vivo

    April 2002-March 2003: postdoctoral researcher,supervisor:
    Prof. Clifford C. Leznoff
    , Department of Chemistry, York University,Canada; Research subject: Multisubstituted phthalonitriles for phthalocyanines synthesis

    Dec. 2003-August, 2004: Research Chemist, Toronto Research Chemicals Inc.(Toronto,Canada)

    March, 2003-present, Research Chemist , Orbital Biochemical Inc. (Toronto,Canada)

  • EDUCATION BACKGROUND
  • Sept.1982-July,1986: B.Sc. specializing in Organic chemistry, Department of Chemistry and Chemical Engineering, Hunan University, P.R. China

    Sept.1989-July,1992: M.Sc., Department of Chemistry and Chemical Engineering, Hunan University, P.R. China; Specialty: Gas Chromatograph Analysis.

    Sept.1992-May,1996: Ph.D., Dept. of Chemical Engineering, Beijing Institute of Technology; Specialty: polydiacetylenes nonlinear optical materials research.


  • REFERENCES
  • Prof. Yuquan Shen, Institute of Chemistry, the Chinese Academy of Sciences, Beijing 100101, P. R. China

    Prof. Congxuan Yu, Department of Chemical Engineering, Beijing Institute of Technology, PO Box 327, Beijing 100081, P. R. China

  • PUBLICATIONS
  • 1. Jianghong Wang, Robert A. McClelland , et al., Syntheses of clozapine-like antipsychotic drugs and their corresponding affinity numbers in vitro/ in vivo, is being prepared for Journal of Medical Chemistry..

    2. Jianghong Wang, Ashot Kh. Khanamiryan and Clifford C. Leznoff, Multisubstituted phthalonitriles for phthalocyanines synthesis, Journal of Porphyrinns and Phthalocyanines, 2004, have be accepted.

    3. Wang, Jiang-Hong; Shen, Yu-Quan; Yu, Cong-Xuan; Si, Jing-Hai. Synthesis and solid-state polymerization of 5-(2-methylthio-4-methylpyrimidin-5-yl)penta-2,4-diyn-1-ol and its derivatives. Perkin Transaction 1 (2000), (9), 1455-1460.

    4. Wang, Jiang-Hong; Shen, Yu-Quan; Yu, Cong-Xuan; Zheng, Jie. The syntheses of a soluble diacetylene and its polymer with push-pull azobenzene and pyrimidine ring attached. Synthetic Metals (2000), 113(1-2), 73-76.

    5 Wang, Jiang-Hong; Shen, Yu-Quan; Si, Jing-Hai. Synthesis and solid-state polymerization of 5-(p-methylthio-o-methyl-pyrimidinyl)-2,4-pentadiyn -1-ol and the third-order optical nonlinearity of its derivatives. Journal of Materials Science (2000), 35(23), 5981-5987.

    6. Wang, Jianghong; Shen, Yuquan; Shi, Zhiwen. Synthesis and characterization of an active styrylthiophene monomer and its polyurethane with second-order optical nonlinearity. Journal of Materials Science (2000), 35(9), 2139-2143.

    7. Wang, Jiang-Hong; Shen, Yu-Quan. Synthesis and fluorescence properties of new derivatives of 4-dicyanomethylene-2,6-dimethyl-4H-pyran. Advanced Materials for Optics and Electronics (2000), Volume Date 1999, 9(4), 129-134.

    8. Wang, Jiang-Hong; Cao, Ya-An; Cao, Chang-Sheng; Shi, Yan-Hui; Shong, Qing; Wang, Li-Jun; Yao, Jian-Nian. Synthesis of a soluble diacetylene with phenylimidazole ring. Chem. Res. Chin. Univ. (2000), 16(4), 324-327.

    9. Wang, Jiang-Hong; Shen, Yu-Quan. Synthesis and fluorescence effects of the derivatives of 4-dicyanomethylene-2,6-dimethyl-4h-pyran. Huaxue Xuebao (2000), 58(8), 1053-1058.

    10. Wang, Jiang-Hong; Shen, Yu-Quan. Synthesis and thermal stability of thioether dianhydride poly(amic acid). Gaodeng Xuexiao Huaxue Xuebao (2000), 21(6), 879-883.

    11. Wang, Ce; Wang, Jianghong; Cao, Cangsheng; Cao, Yaan; Yao, Jiangnian. Synthesis of a soluble diacetylene derivative with imidazole ring. Book of Abstracts, 219th ACS National Meeting, San Francisco, CA, March 26-30, 2000 (2000), POLY-156.

    12. Wang, Jianghong; Shen, Yuquan. Synthesis and processing of improved organic second-order nonlinear optical materials for application in photonics. Gaojishu Tongxun (2000), 10(5), 104-106.

    13. Fu, Wei; Feng, Ji-Kang; Ren, Ai-Min; Sun, Chia-Cung; Wang, Jiang-Hong; Shen, Yu-Quan. Theoretical study on design of molecules with first hyperpolarizabilities based on barbituric acid. Gaodeng Xuexiao Huaxue Xuebao (2000), 21(12), 1892-1895.

    14. Fu, Wei; Feng, Ji-Kang; Yu, Kun-Qian; Ren, Ai-Min; Wang, Jiang-Hong; Shen, Yu-Quan. Theoretical studies on NLO properties of push-pull multi-cycle electro-optical polymer intermediates including thiophene ring. Chin. J. Chem. (2000), 18(6), 820-827.

    15. Fu, Wei; Feng, Ji-kang; Ren, Ai-min; Cui, Meng; Jin, Hong-wei; Wang, Jiang-hong; Shen, Yu-quan. Molecular device of new pull-push electro-optical polymer intermediates with second-order NLO properties. Fenzi Kexue Xuebao (2000), 16(1), 5-11.

    16. Fu, Wei; Feng, Ji-Kang; Ren, Ai-Min; Sun, Chia-Cung; Wang, Jiang-Hong; Shen, Yu-Quan. Theoretical study and design of multisubstituted barbituric acid derivatives with third-order NLO susceptibility. Jiegou Huaxue (2000), 19(4), 306-310.

    17. Fu, Wei; Feng, Ji-Kang; Ren, Ai-Min; Cui, Meng; Jin, Hong-Wei; Wang, Jiang-Hong; Shen, Yu-Quan. Theoretical studies of molecules with nonlinear optical third-order susceptibilities on pull-push multi-ring electro-optical polymer intermediates including thiophene ring. Gaodeng Xuexiao Huaxue Xuebao (2000), 21(5), 771-775.

    18. Fu, Wei; Feng, Ji-Kang; Ren, Ai-Min; Sun, Xiu-Yun; Jin, Hong-Wei; Wang, Jiang-Hong; Shen, Yu-Quan. Theoretical studies on second-order nonlinear optical properties of a series of new push-pull polycyclic conjugated molecules. Gaodeng Xuexiao Huaxue Xuebao (2000), 21(4), 616-619.

    19. Fu, Wei; Feng, Ji-Kang; Ren, Ai-Min; Sun, Xiu-Yun; Jin, Hong-Wei; Wang, Jiang-Hong; Shen, Yu-Quan. Theoretical studies on the third-order nonlinear optical property and design of some organic NLO materials. Jiegou Huaxue (2000), 19(1), 57-63.

    20. Zhao, Yu-Xia; Li, Zhao; Wang, Jiang-Hong; Liu, Shi-Xiong; Qiu, Ling; Zhai, Jian-Feng; Zhou, Jia-Yun; Shen, Yu-Quan. Synthesis of highly active thiophene ring-containing photic chromophores. Huaxue Xuebao (2000), 58(4), 486-490. CODEN: HHHPA4 ISSN:0567-7351. CAN 133:89387 AN 2000:304787 CAPLUS

    21. Wang, Jiang-Hong; Zhai, Jian-Feng; Zhou, Jia-Yun; Zhao, Yu-Xia; Shen, Yu-Quan. Synthesis and characterization of a novel styrylthiophene monomer and corresponding polyurethane for NLO materials. Chin. J. Polym. Sci. (1999), 17(4), 359-365.

    22. Wang, Jiang-Hong; Shen, Yu-Quan; Yu, Cong-Xuan. Synthesis of azobenzene and pyrimidine-substituted diacetylenes as nonlinear optical material. Youji Huaxue (1999), 19(3), 282-287.

    23. Wang, Jiang-Hong; Zhou, Jia-Yun; Zhang, Xin-Xin; Zhai, Jian-Feng; Li, Zhao; Shen, Yu-Quan; Xu, Gang. Synthesis of a styrylthiophene monomer and corresponding polyurethane and their optical nonlinearity. Gaodeng Xuexiao Huaxue Xuebao (1999), 20(2), 237-242.

    24. Wang, Jianghong; Yu, Congxuan; Shen, Yuquan; Chen, Guangju. Polymerization properties of three butadiyne derivatives. Huaxue Wuli Xuebao (1999), 12(1), 73-76.

    25. Shen Yuequan , Zhao Yuxia, Li Zhao, Wang Jianghong Liu Shixiong, Qiu Ling, Zhai Jianfeng, Zhou Jiayun, The Synthesis of Highly Active Thiophene Ring Contaning Chromophore Components for Photoic Polymers Based on A Newly Designed Route, Journal of Chemical Society, Perkin Transactions 1, Issue 24, pp3691-3696, 1999.

    26. Shen Yuequan ,Li Zhao, Zhao Yuxia, Zhai Jianfeng, Zhou Jiayun, Wang Jianghong, A simple approach for estimating asorption loss in organic thin solid films, Journal of Nonlinear Optical Physics & Materials, 1999, Vol. 8 (4), 519-525

    27. Wang, Jianghong; Shen, Yuquan; Yu, Congxuan; Zhu, Peiwang; Sun, Yunan. All optical channel waveguide of PDMA/PMMA composite. Gongneng Gaofenzi Xuebao (1998), 11(3), 361-366.

    28. Wang, Jianghong; Shen, Yuequan; Zhai, Jianfeng. Synthesis and characterization of a transparent polyamic acid containing thioether segments. Gongneng Gaofenzi Xuebao (1998), 11(4), 521-524.

    29. Wang, Jianghong; Shen, Yuquan; Yu, Congxuan; Zhu, Peiwang; Si, Jinhai. Third-order nonlinear optical characteristics of several novel diacetylene derivatives substituted with heterocyclic rings. Gaojishu Tongxun (1998), 8(3), 33-37.

    30. Wang, Jianghong; Shen, Yuquan; Yu, Congxuan; Song, Yinglin. Optical limiting effect resulted from single photon absorption in PDA composites. Zhongguo Jiguang (1998), A25(12), 1091-1094.

    31. Wang, Jianghong; Li, Zhao; Qiu, Ling; Zhai, Jianfeng; Shen, Yuequan; Zhou, Jiayun; Shi, Zhiwen. Synthesis and characterization of a novel styrylthiophene monomer and corresponding heterocyclic polymer for NLO materials. Proc. SPIE-Int. Soc. Opt. Eng. (1998), 3556(Electro-Optic and Second Harmonic Generation Materials, Devices, and Applications II), 57-65.

    30. Wang, Jianghong; Yu, Congxuan; Shen, Yuquan. Progress of organic third-order nonlinear optical materials. Gongneng Cailiao (1998), 29(6), 566-573.

    32. Wang, Jianghong; Yu, Congxuan; Song, Yinglin. Characteristics of reversible optical storage of butidiacetylene derivative with pyrimidine ring and azobenzene substituent. Gongneng Cailiao (1998), 29(5), 546-549.

    33. Wang, Jianghong; Yu, Congxuan; Liu, Jingyong; Shen, Yuquan. Synthesis of two 4-N,N-dimethylaminoazobenzene-4'-sulfonate derivatives and evaluation of their d33 in polarized polymer films. Beijing Ligong Daxue Xuebao (1997), 17(1), 50-54.

    34. Ren, Ai-Min; Feng, Ji-Kang; Xiao, Chang-Yong; Sun, Chia-Chung; Wang, Jiang-Hong; Yu, Cong-Xuan. Theoretical studies on the nonlinear optical properties of new diacetylene derivatives with azobenzene substituents. Gaodeng Xuexiao Huaxue Xuebao (1997), 18(4), 609-614.

    35. Wang, Jianghong; Yu, Congxuan; Shen, Yuquan. Synthesis and characterization of nonlinear optical material of substituted diacetylenes with azophenyl group and pyrimidine ring. J. Beijing Inst. Technol. (Engl. Ed.) (1996), 5(2), 123-129.

    36. Wang, Jianghong; Yu, Congxuan; Chen, Guangju; Huang, Yuanhe. The quantum chemical study on polymeric properties of several diacetylene derivatives. Beijing Ligong Daxue Xuebao (1996), 16(2), 160.

    37. Xu, Hongyao; Guang, Shanyi; Jiang, Minhua; Wang, Jianghong; Yu, Congxuan. Fabrication and measurement of polymer waveguides. Gongneng Cailiao (1995), 26(Suppl.), 84-7.

    38. Xu, Hongyao; Wang, Jianghong; Zhu, Peiwang; Yu, Congxuan; Song, Yingling; Li, Chunfei; Li, Yurui; Sun, Yunan; Cui, Fang; et al. a novel synthesis method, nonlinear optical properties of (4-n-butoxycarbonyl)methyl urethane polydiacetylene. Proc. SPIE-Int. Soc. Opt. Eng. (1994), 2321(Second International Conference on Optoelectronic Science and Engineering '94, 1994), 10-13.

    39. Yu, Congxuan; Liu, Jingyong; Xu, Hongyao; Wang, Jianghong; Zu, Peiwang; Feng, Jinsheng. Third-order nonlinear optical properties for substituted diphenylpolyene and substituted polydiacetylene. Gaojishu Tongxun (1994), 4(5), 15-20.


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