How To Obtain Low Dose Naltrexone (LDN)
There are two basic approaches to obtaining LDN. The first involves getting a prescription for the drug from a physician and having it filled by a compounding pharmacy. The second involves purchasing 50 mg Naltrexone tablets from an online supplier and converting them yourself to LDN.
You can obtain a prescription for LDN by contacting Crystal Nason, who maintains a worldwide list of physicians who prescribe LDN and of pharmacies that compound it. Her e-mail address is
For information about obtaining LDN in the United Kingdom, contact the LDN Research Trust at
Additional information about obtaining LDN in the UK may be obtained by contacting:
You may find a physician in your vicinity willing to prescribe LDN by contacting the American College for Advancement in Medicine, a non-profit organization that claims to be the voice of integrative medicine. It represents more than 1,000 physicians in 30 countries. For more information, visit
You may also try asking a nearby compounding pharmacist for the names of doctors who prescribe LDN. To find such a pharmacist, contact the International Academy of Compounding Pharmacists at
You can find a number of pharmacies known to be reliable compounders of LDN listed at
If you chose to use a U.S. pharmacy that is not on the list, make sure it belongs to an organization called Professional Compounding Centers of America.
The least expensive and perhaps the most convenient option for obtaining LDN is to purchase 50 mg Naltrexone tablets online without a prescription from such online suppliers as
At the present time, Naltrexone is manufactured by a number of different companies under the following trade names:
Nalorex (manufactured by Bristol-Myers-Squibb in the UK)Making your own LDN avoids problems that sometimes arise when pharmacies compound LDN with fillers to which one is allergic or that cause delayed release of the Naltrexone. In addition, pharmacies cannot always be relied upon to compound LDN correctly, as this site illustrates:
Nodict (manufactured by Sun Pharma in India)
Naltima (manufactured by INTAS in India)
Narpan (manufactured by Duopharma in Malaysia)
Antaxone (manufactured by Pharmazam in Spain)
Celupan (manufactured by Lacer in Spain)
Narcoral (manufactured by Siton in Italy)
Nemexin, Revez, Naltrexona, and Naltrexonum (manufactured by Bristol-Myers-Squibb in Germany)
Other advantages of making your own LDN include the fact that compounding is expensive and time consuming, and liquids are the preferred dosage form for children and for people who have difficulty swallowing capsules or tablets. Also, if your doctor is willing to prescribe Naltrexone, your health insurance is more likely to cover the tablet than the compounded form.
Once you have a supply of 50 mg Naltrexone tablets, you can convert them as needed to LDN. To do so, fill a graduated cylinder with 50 ml of distilled water (unlike tap or spring water, distilled water contains no impurities that could potentially react with and thus reduce Naltrexone's effectiveness). Pour the water from the graduate into a 4 oz amber glass jar with a tight-fitting lid. Then add a 50 mg Naltrexone tablet. The tablet will mostly dissolve in about five to ten minutes. Since not all of the tablet is soluble in water, instead of yielding a clear solution, the result will be a cloudy suspension. It must be shaken each time before use to evenly disperse all the undissolved particles. One ml of the (shaken) suspension will contain one mg of Naltrexone. You can use a graduated baby medicine dropper to measure out the dose you need. For greater accuracy, some people prefer to use a regular medicine dropper and add the LDN drop-by-drop into a 5 ml graduated cylinder. It is also possible to draw up fairly accurate doses using an oral dosage syringe.
Once a drug passes from a solid to a liquid state, its shelf life can decrease dramatically. Therefore, do not make more than 50 ml of liquid Naltrexone at a time, store it in the refrigerator, and do not keep it for more than a two months. The fresher the preparation, the better. Be sure to shake the liquid LDN well before using, and keep it from direct exposure to sunlight.
The baby medicine dropper should be available in the infant/baby section of your local pharmacy. If you ask politely and are lucky, the pharmacist may (as a gesture of good will) give you an empty 4 oz amber glass jar. Distilled water is sold by most pharmacies, as well as by supermarkets, hardware stores, and convenience stores.
There are those who suggest using a baby bottle in which to prepare liquid LDN. That is not a good practice. Graduations on baby bottles are only approximations and may produce an inaccurate dosage. In addition, most baby bottles are made of clear plastic and contain a toxic chemical called Bisphenol A (BPA), which has been linked to a number of health problems. Also, many drugs are degraded by exposure to light and prolonged contact with plastic.
Because liquid Naltrexone has a very unpleasant taste, you may wish to disguise it in something like fruit or vegetable juice. I add it to a cup of luke warm, well-sweetened Chamomile tea (a sleep aid).
The recommended dosage of LDN for the average adult is 4.5 mg (higher amounts are generally considered counterproductive). If you are using liquid LDN, that would equate to 4.5 ml. It should be taken between 9 pm and 3 am. To control for changes between Daylight Savings and Standard Time, some authorities recommend taking LDN between 10 pm and 2 am.
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Hoping you find the information in this website both helpful and hopeful, I am,
Dudley Delany, R.N., M.A., D.C.
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Why I Became An Advocate For Low Dose Naltrexone
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